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Multidisciplinary Expert Opinion on the Treatment Consensus for Patients with EGFR Mutated NSCLC with Brain Metastases

原文:2019年 发布于 Crit Rev Oncol Hematol 浏览量:308 原文链接

作者:

归属分类: 所属人体系统: 呼吸 | 分类: 肺癌

关键词: Brain Metastases Consensus Diagnosis EGFR Mutation Management NSCLC Recommendation Treatment

指南简介

The presence of an epidermal growth factor receptor (EGFR) mutation is associated with higher incidence of brain metastases in patients with non-small cell lung cancer (NSCLC); however, patients with synchronous brain metastases at diagnosis have generally been excluded from clinical trials. As there is limited clinical evidence for managing this patient population, a multidisciplinary group of Spanish medical and radiation oncologists, and neuro-oncologist with expertise treating brain metastases in lung cancer patients met with the aim of reaching and developing an expert opinion consensus on the management of patients with EGFR mutated NSCLC with brain metastases. This consensus contains 26 recommendations and 20 conclusion statements across 21 questions in 7 areas, as well as a first-line treatment algorithm.