In order to improve the overall therapeutic effect of gallbladder cancer in China, Branch of Biliary Surgery, Chinese Surgical Society and Chinese Committee of Biliary Surgeons have formulated the guideline for the diagnosis and treatment of gallbladder carcinoma (2019 edition) . The guideline provided an overview of the evidence on epidemiological risk factors, treatment and follow-up strategies for patients with gallbladder cancer.It also updated the new TNM stage and proposed the clinical classification of gallbladder cancer for the first time. The guideline highlighted the importance of accurate prediction of TNM stage and type of gallbladder cancer based on modern high-quality imaging technology and endoscopic techniques.The idea of comprehensive treatment should be established as the fundamental principle for patients with advanced gallbladder cancer, and a multidisciplinary approach is recommended to make optimal clinical decisions. Standard radical surgical treatment should be delivered by a team of experienced hepato-pancreato-biliary surgeons and pathologists.The combination regimens of chemotherapy, radiotherapy, targeted therapy and immunotherapy for gallbladder cancer have shown promise in improving prognosis. Further research is still needed to confer greater survival benefits to patients with gallbladder cancer.