Breast cancer is the most common neoplasm in women worldwide, as well as in our country. However, in Mexico there are differences that are important to identify and individualize in order to improve the outcomes of women suffering from this disease. Thus, the purpose of this 8th consensus review is to provide a national updated guideline, based on the best scientific evidence, and adjusted to the heterogeneity of our health system and to the existing needs and therapeutic coverage. Worldwide, breast cancer treatment is acknowledged as being multimodal, and therefore it requires a multidisciplinary group to help make the best therapeutic decisions. Hence, the conclusions of this consensus provide the best evidence to guide surgical, radiotherapy and systemic treatment, based on patient, tumor and the health system characteristics. Finally, in this edition, special emphasis is made on the need to establish an early and accurate diagnosis and to start the indicated therapy as soon as possible, since the delay in treatment implementation has been shown to negatively affect the survival rate.