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Rare Non-Hodgkin Lymphoma of Childhood and Adolescence: a Consensus Diagnostic and Therapeutic Approach to Pediatric-type Follicular Lymphoma, Marginal Zone Lymphoma, and Nonanaplastic Peripheral T-cell Lymphoma

原文:2020年 发布于 Pediatr Blood Cancer 67卷 第8期 e28416 浏览量:277 原文链接

作者:

归属分类: 所属人体系统: 循环 | 分类: 淋巴瘤

关键词: Follicular Lymphoma Marginal Zone Lymphoma Non-Hodgkin Lymphoma Peripheral T-cell Lymphoma Rare.

指南简介

Pediatric-type follicular (PTFL), marginal zone (MZL), and peripheral T-cell lymphoma (PTCL) account each for <2% of childhood non-Hodgkin lymphoma. We present clinical and histopathological features of PTFL, MZL, and few subtypes of PTCL and provide treatment recommendations. For localized PTFL and MZL, watchful waiting after complete resection is the therapy of choice. For PTCL, therapy is subtype-dependent and ranges from a block-like anaplastic large cell lymphoma (ALCL)-derived and, alternatively, leukemia-derived therapy in PTCL not otherwise specified and subcutaneous panniculitis-like T-cell lymphoma to a block-like mature B-NHL-derived or, preferentially, ALCL-derived treatment followed by hematopoietic stem cell transplantation in first remission in hepatosplenic and angioimmunoblastic T-cell lymphoma.