Since December, 2019, the corona virus disease 2019 (COVID-19) spread rapidly from Wuhan, Hubei Province. In order to reduce and prevent cross-over infection during interventional diagnosis and treatment of tumor patients, the Interventional Oncology Branch of China Anti-Cancer Association organized experts to compile this corresponding expert consensus, focused on the key points for COVID-19 prevention, including management of outpatient, inpatient and interventional operating room during the epidemic period of COVID-19.